Segundo, I have my 2x10 hardtail mtb on my saris H3 right now and its fine. When it comes follow the pictures for setting up the driver and different spacers for qr skewer/thru axle etc. I originally had my road bike on it but switched to MTB and had to reconfigure the spacers etc. Really like the trainer though, picked it up about this time last year.Hmm. I do have an 11-speed mtb cassette, RD and shifter. So I'd leave the DuraAce crankset 53-38 and change the chain to an 11-speed chain?
I don't like spending $70 to bring my brand new brainer trainer to the cave era, but it's an option. I know that everything works with that drive train.